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Early detection and removal of cancer is important to improving patient care outcomes, and in the United States, regular CRC screenings are recommended for vulnerable populations and individuals over the age of 50 up to 75 years of age.
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CRC incidence rates vary according to age and sex, and CRC is the most common cancer in females and fourth most common cancer in males aged 65 years and older. In 2017, the incidence of CRC in Korea was 29.7 per 100,000 individuals, making it the third most common cancer in the country after thyroid and stomach cancer. However, the involvement of individual serum cholesterol levels and continuity of statin therapy in CRC risk remain unknown. Physical activity, diet, individual behavioral factors, and obesity are associated with CRC risk, and dyslipidemia and abnormal glucose metabolism are positively associated with CRC risk. Low-density lipoprotein cholesterol MPR,Ĭolorectal cancer (CRC) is the third most common cancer and ranks as the second most common cause of cancer-related death worldwide. International Classification of Diseases LDL-C, However, the funding sources did not have interventions such as study design and data interpretation.Ĭompeting interests: The authors have declared that no competing interests exist. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: The data used in this study are third party data from NHIS ( ) and can be accessed following the protocol outlined in the Methods section.įunding: This research was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (NRF-2019R1G1A1006476). Received: SeptemAccepted: ApPublished: April 23, 2021Ĭopyright: © 2021 Han, Kim.
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Citation: Han K-T, Kim S (2021) Do cholesterol levels and continuity of statin use affect colorectal cancer incidence in older adults under 75 years of age? PLoS ONE 16(4):Įditor: Antonio Palazón-Bru, Universidad Miguel Hernandez de Elche, SPAIN